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Equipment
Instrumentation available at FABI
LC-MS
- Waters Acquity UPLC I class system coupled to Xevo G2 Q-TOF mass spectrometer
HPLC/UHPLC instruments
- Thermo Scientific ultrahigh pressure liquid chromatography (UHPLC) system with PDA detection
- Shimadzu gradient ultrafast liquid chromatography (UFLC) system with PDA detection
- Merck-Hitachi Lachrom Elite gradient HPLC system with PDA detection and ELSD detection (Alltech ELSD 2000)
- Two Merck-Hitachi Lachrom gradient HPLC systems with UV detection
SFC instruments
- UPC² (Waters): Supercritical fluid chromatography system with PDA detection
- Thar Method station II: Supercritical fluid chromatography system with PDA detection
Capillary electrophoresis/Capillary electrochromatography
- Capillary electrophoresis Agilent HP3DCE system with PDA detection
- Two Capillary electrophoresis Beckman P/ACE MDQ systems with PDA detection (one also with LIF detection)
- Unimicro-Trisep 2100 GV Pressurized capillary electrochromatography system with UV detection
Spectroscopy
- Bran+Luebbe InfraAlyzer 500Near infrared spectrophotometer
- Shimadzu UV-2101PC UV/Vis spectrophotometer
Miscellaneous
- Ecocell 111 liter incubator
- Sartorius Arium Pro UV ultrapure water system
- Haskel DSHF-302-S High pressure liquid pump
- Capillary burner EK 1.2, Capital HPLC
- Harrick Plasma cleaner/sterilizer
Topics
- Chiral Separations, Monolithic stationary phases, Miniaturized separation techniques, Capillary Electrochromatography, High Performance Liquid Chromatography, Capillary Electrophoresis, Supercritical Fluid Chromatography, Experimental design (Debby Mangelings)
- Method development and optimisation; Method validation (robustness testing); Separation techniques (e.g. HPLC, CE, CEC); Chemometrics in separation science, QSAR, QSRR and QSSR; Herbal fingerprints, Drug-impurity profiling, Chiral separations, Metabolomics (Yvan Vander Heyden)
- Neuropeptides, Miniaturized UHPLC-ESI-MS/MS (Jana Bongaerts)
- SFC and LC coupled with circular dichroism (CD) detector, Molecular Dynamics and Quantitative Structure Enantioselective Retention Relationship (QSERR) models (Pieter De Gauquier)
- Skin permeability modelling in HPLC, Micellar liquid chromatography (Yasmine Grooten)
- Computation and Medicinal Chemistry: Developing methods for Computer-Aided Drug Design (Jordy Peeters)
- Chiral separation, Impurity determination, CE, SFC (Petra Riasova)
- Chemometrics, Metabolomics, Classification and discrimination of chromatographic fingerprints, UPLC-ESI QTof MS (Karen Segers)