Equipment
Instrumentation available at FABI
LC-MS
- Waters Acquity UPLC I class system coupled to Xevo G2 Q-TOF mass spectrometer
HPLC/UHPLC instruments
- Thermo Scientific ultrahigh pressure liquid chromatography (UHPLC) system with PDA detection
- Shimadzu gradient ultrafast liquid chromatography (UFLC) system with PDA detection
- Merck-Hitachi Lachrom Elite gradient HPLC system with PDA detection and ELSD detection (Alltech ELSD 2000)
- Two Merck-Hitachi Lachrom gradient HPLC systems with UV detection
SFC instruments
- UPC² (Waters): Supercritical fluid chromatography system with PDA detection
- Thar Method station II: Supercritical fluid chromatography system with PDA detection
Capillary electrophoresis/Capillary electrochromatography
- Capillary electrophoresis Agilent HP3DCE system with PDA detection
- Two Capillary electrophoresis Beckman P/ACE MDQ systems with PDA detection (one also with LIF detection)
- Unimicro-Trisep 2100 GV Pressurized capillary electrochromatography system with UV detection
Spectroscopy
- Bran+Luebbe InfraAlyzer 500Near infrared spectrophotometer
- Shimadzu UV-2101PC UV/Vis spectrophotometer
Miscellaneous
- Ecocell 111 liter incubator
- Sartorius Arium Pro UV ultrapure water system
- Haskel DSHF-302-S High pressure liquid pump
- Capillary burner EK 1.2, Capital HPLC
- Harrick Plasma cleaner/sterilizer
Recent projects
Bilateral cooperation within the framework of a joint doctoral project: benchfee for joint PhD VUB -CHARLES UNIVERSITY CZECH REPUB, RIASOVA , Petra
22/03/2019
OZR3383: Bilateral cooperation within the framework of a joint doctoral project: benchfee for joint PhD VUB -CHARLES UNIVERSITY CZECH REPUB, RIASOVA , Petra
Mangelings, D.
22/03/19 → 21/03/22
Project : Fundamental
Cofinancing OZR FWO Hercules MZW equipment: GHz-THz VNA measurement infrastructure: from benchtop to portable instruments serving advanced sensor solutions in a variety of multi-disciplinary application domains.
11/04/2018
OZR3251: Cofinancing OZR FWO Hercules MZW equipment: GHz-THz VNA measurement infrastructure: from benchtop to portable instruments serving advanced sensor solutions in a variety of multi-disciplinary application domains.
Stiens, J. , Peeters, E. , Maes, D. , Vander Heyden, Y. , Mangelings, D...
Modern chiral separation strategies: a tool to facilitate the development of QSRR models
07/02/2018
FWOKN305: Modern chiral separation strategies: a tool to facilitate the development of QSRR models
Mangelings, D. & Vander Heyden, Y.
1/01/18 → 31/12/18
Project : Fundamental
Development of a supercritical fluid chromatographic system to predict the skin permeability of pharmaceutical compounds.
22/09/2017
FWOTM851: Development of a supercritical fluid chromatographic system to predict the skin permeability of pharmaceutical compounds.
Vander Heyden, Y. , Mangelings, D. & Grooten, Y.
1/10/17 → 30/09/21
Project : Fundamental
VLIR UOS TEAM 2017 : Quality Control and Therapeutic Valorization of Moroccan Argan oils: the impact of the sustainability of the human development.
24/01/2017
VLIR345: VLIR UOS TEAM 2017 : Quality Control and Therapeutic Valorization of Moroccan Argan oils: the impact of the sustainability of the human development.
Vander Heyden, Y. , De Cupere, F. & Motmans, J.
1/01/17 → 31/08/22
Project :...
Topics
- Chiral Separations, Monolithic stationary phases, Miniaturized separation techniques, Capillary Electrochromatography, High Performance Liquid Chromatography, Capillary Electrophoresis, Supercritical Fluid Chromatography, Experimental design (Debby Mangelings)
- Method development and optimisation; Method validation (robustness testing); Separation techniques (e.g. HPLC, CE, CEC); Chemometrics in separation science, QSAR, QSRR and QSSR; Herbal fingerprints, Drug-impurity profiling, Chiral separations, Metabolomics (Yvan Vander Heyden)
- Neuropeptides, Miniaturized UHPLC-ESI-MS/MS (Jana Bongaerts)
- SFC and LC coupled with circular dichroism (CD) detector, Molecular Dynamics and Quantitative Structure Enantioselective Retention Relationship (QSERR) models (Pieter De Gauquier)
- Skin permeability modelling in HPLC, Micellar liquid chromatography (Yasmine Grooten)
- Computation and Medicinal Chemistry: Developing methods for Computer-Aided Drug Design (Jordy Peeters)
- Chiral separation, Impurity determination, CE, SFC (Petra Riasova)
- Chemometrics, Metabolomics, Classification and discrimination of chromatographic fingerprints, UPLC-ESI QTof MS (Karen Segers)